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The 19th Annual Meeting of JSIT |
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| Special Lecture 1 |
| Overview and Application of the WHO/IPCS Harmonized Guidance for Immunotoxicity: Risk Assessment for Chemicals |
Henk van Loveren |
Maastricht University, National Institute of Public Health and the Environment, The Netherlands |
| Special Lecture 2 |
| New with old in immunotoxicological research ---- What has been and what shall be in our Society of Immunotoxicology |
Motoyasu Ohsawa |
Hatano Research Institute, Food and Drug Safety Center, Hadano, Japan. |
| Master’s LectureP |
| Molecular mechanism of fatigue and relationship between immunotoxicology and fatigue |
Kazuhiro Kondo |
Department of Virology, The Jikei University School of Medicine |
| Master’s Lecture 2 |
| Pathological linkage of metabolic disease and autoimmunity by Apoptosis Inhibitor of Macrophage (AIM) |
Toru Miyazaki |
Laboratory of Mlecular Biomedicine for Pathogenesis, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo, Japan |
| Awards Lectures <JSIT RESARCH AWARD > |
| Study on the aggravation mechanism of allergy induced by environmental chemicals |
Eiko Koike |
Center for Environmental Health Sciences, National Institute for Environmental Studies, Tsukuba, Japan |
| Awards Lectures <JSIT RESARCH AWARD > (Sympojium) |
| Immunological analysis of asbestos-exposed people for identification of new diagnostic markers |
ZYasumitsu Nishimura (1), Naoko Kumagai-Takei (1), Hidenori Matsuzaki(1), Suni Lee (1) , Megumi Maeda (2) , Takumi Kishimoto(3) , Takemi Otsuki(1) |
(1)Department of Hygiene, Kawasaki Medical School, Kurashiki, Japan , (2)Laboratory of Functional Glycobiochemistry, Department of Biofunctional Chemistry, Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan , (3)Okayama Rosai Hospital, Okayama, Japan |
| Symposium@ “Progress in research for immunotoxicology” |
| Topics of research on sick house syndrome, with special reference to an immunotoxicological aspect |
Kou Sakabe |
Department of human structure and function, Tokai University School of Medicine, Kanagawa, Japan |
| Advances in gut immunity to gastrointestinal nematode infections |
Kenji Ishiwata |
Department of Tropical Medicine, The Jikei University School of Medicine, Tokyo, Japan |
| Workshop@"In vitro immunotoxicology" |
| Current Trend on In Vitro Immunotoxicology in EU |
Emanuela Corsini |
Laboratory of Toxicology, Dipartimento di Scienze Farmacologiche e Biomolecolari, Faculty of Pharmacy, Università degli Studi di Milano, Milan, Italy |
| Development and application of an in vitro skin sensitization test named h-CLAT based on alteration of dendritic cell surface markers expression |
Hitoshi Sakaguchi |
Safety Science Reserach Laboratories, Kao Corporation, Tochigi, Japan |
| Study on safety assessment for sensitization using alternative methods |
Taro Ashikaga |
Research Center, Shiseido Co., Ltd., Kanagawa, Japan |
| Development of assay system for immunotoxicity using cytokine reporter cells (Multi-ImmunoTox assay) |
Setsuya Aiba |
Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan |
| Irradiation of light emitting diode at 850 nm inhibits T cell-induced cytokine expression |
Kyung Ah Cheong, Chang-hyun Kim, Yun-Seok Choi, ZAi-Young Lee |
Department of Dermatology, Dongguk University Ilsan Hospital, South Korea |
| Oral Presentations |
| Effects of intratracheal exposure to phthalates in an allergic asthma |
ZRie Yanagisawa(1), Eiko Koike(1), Tin Tin Win Shwe(1), Takamichi Ichinose(2), Hiroshi Takano(3) |
(1)Center for Environmental Health Sciences, National Institute for Environmental Studies, Japan , (2)Department of Health Sciences, Oita University of Nursing and Health Sciences, Notsuharu, Oita, Japan , (3)Graduate School of Engineering, Kyoto University, Kyoto, Japan |
| Expression of neuroimmune biomarkers in hypothalamus of allergic mice after early phthalate exposure |
ZTin Tin Win Shwe(1), Rie Yanagisawa(1), eiko Koike(1), Hiroshi Nitta(1), Hirohisa Takano(2) |
(1)Center for Environmental Health Sciences, National Institute for Environmental Studies, Tsukuba, Japan , (2)Department of Environmental Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan |
| Analysis of serum IgE from patients sensitized to acid-hydrolyzed wheat protein in facial soap |
Rika Nakamura(1), Ryosuke Nakamura(1), Shinobu Sakai(1), Reiko Adachi(1), Yasuharu Itagaki(2), Yuma Fukutomi(3), Reiko Teshima(1) |
(1)Div. Novel Foods Immunochem., Natl. Inst. Health Sci., Tokyo, Japan , (2)Dept. Health Nutr., Hokkaido Bunkyo Univ., Hokkaido, Japan , (3)Clin. Res. Ctr. Allergy Rheumatol., Sagamihara Natl. Hosp., Kanagawa, Japan |
| Size-dependent effect of amorphous silica nanoparticles on atopic dermatitis |
ZYasuo Yoshioka(1), Toshiro Hirai(1), Shin-ichi Tsunoda(2),(3), Hiromi Nabeshi(4), Tomoaki Yoshikawa , Yasuo Tsutsumi(1),(2),(3) |
(1)Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan , (2)Laboratory of Biopharmaceutical Research, National Institute of Biomedical Innovation, Osaka, Japan , (3)MEI center, Osaka University, Osaka, Japan , (4)National Institute of Health Science, Tokyo, Japan |
| Applicability of CBA/J mice to the Local Lymph Node Assay: BrdU-ELISA. |
ZToshio Kobayashi(1), Junichi Kikuchi(1), YasuhiroTsubokura(1), Masanori Taruki(2), Syozo Ajimi(1), Masahiro Takeyoshi (3) |
(1)CERI Hita, Chemicals Evaluation and Research Institute, Japan , (2)CERI Kurume , Chemicals Evaluation and Research Institute, Japan. , (3)Chemicals Assessment and Research Center, Chemicals Evaluation and Research Institute, Japan. |
| Sensitization study by qualitative structure-toxicity relationships (QSTR) approaches |
ZKazuhiro Sato, Yukinori Kusaka |
Department of Environmental Health, School of Medicine, University of Fukui, Fukui, Japan |
| Effects of AhR agonists on IL-17 and IL-22 gene expressions in mouse T lymphoma EL4 cells |
ZHiroyuki Kojima(1), Ryuta Muromoto(2), Miki Takahashi(2), Shinji Takeuchi(1), Tadashi Matsuda(2) |
(1)Hokkaido Institute of Public Health, Sapporo, Japan , (2)Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan |
| Effects of inorganic arsenite on the signal pathway evoked by ATP exposure |
ZDaigo Sumi, Hideta Okada, Kuniko Yogi, Hideki Miyataka, Seiichiro Himeno |
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan |
| Continuous exposure of asbestos accelerates cell cycle progression in MT-2 Cell |
ZSuni Lee(1), Hidenori Matsuzaki(1) , Megumi Maeda(2), Naoko Kumagai-Takei(1), Yasumitsu Nishimura(1), Takemi Otsuki(1) |
(1)Department of Hygiene, Kawasaki Medical School, Kurashiki, Japan , (2)Lab. Functional Glycobiochemistry, Dept. Biofunctional Chemistry, Graduate School of Environmental and Life Science, Okayama Univ., Okayama, Japan |
| Molecular mechanisms of alteration of MT-2 cells induced by long term exposure to asbestos. |
ZHidenori Matsuzaki(1), Suni Lee(1), Megumi Maeda(2) , Naoko Kumagai-Takei(1), Yasumitsu Nishimura(1), Takemi Otsuki(1) |
(1)Department of Hygiene, Kawasaki Medical School, Kurashiki, Japan , (2)Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan |
| Functional analysis of CD8+ lymphocytes in patients with pleural plaque or malignant mesothelioma |
ZNaoko Kumagai-Takei, Yasumitsu Nishimura, Hidenori Matsuzaki, Suni Lee, Takemi Otsuki |
Department of Hygiene, Kawasaki Medical School, Kurashiki, Japan |
| Alteration of cellular characterization caused by continuous exposure of crocidolite or chrysotile on human T cell line |
Megumi Maeda(1), ZTakemi Otsuki(2), Hidenori Matsuzaki(2), Suni Lee(2), Naoko Takei(2), Yasumitsu Nishimura(2) |
(1)Lab. Funct. Glycobiochem. Dept. Biofunct. Chem., Div. Agricult. Life Science, Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan , (2)Department of Hygiene, Kawasaki Medical School, Kurashiki, Japan |
| Commercially available drink-induced anaphylaxis: analyzed using basophil activation test (BAT) and histamine release test |
ZMasao Yamaguchi(1), Yusuke Tanaka(1), Yuko Nakase(1), Naoya Sugimoto(1), Takako Toda(1), Yasuhiro Kojima(1), Asae Kamiyama(1), Hisanao Yoshihara(1), Michio Kuramochi(1), Hiroyuki Tashimo(1), Hidenori Arai(1), Ayako Kawakami(2), Hiroshi Akiyama(3), Hiroyuki Nagase(1), Ken Ohta(1),(4) |
(1)Division of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, (2)Publish Health Insurance Association, (3)National Institute of Health Sciences, (4)National Hospital Organization Tokyo National Hospital, Tokyo, Japan |
| Mechanisms of aggravation atopic dermatitis by environmental immunosuppressive chemicals in NC/Nga mice |
ZTomoki Fukuyama, Tadashi Kosaka, Lisa Miyashita, Risako Nishino,Koichi Hayashi, Hideo Ueda, Takanori Harada |
The Institute of Environmental Toxicology (IET), Ibaraki, Japan |
| Prior oral exposure to environmental immunosuppressive agents aggravates OVA allergen-induced allergic asthma in NC/Nga mice |
ZRisako Nishino, Tomoki Fukuyama, Lisa Miyashita, Koichi Hayashi, Hideo Ueda,Tadashi Kosaka |
The Institute of Environmental Toxicology, Ibaraki, Japan |
| Change of lactoperoxidase in saliva by thalassotherapy |
ZRika Watanabe,Takahiro Sakuta, Mami Kawaguchi, Kuniaki Takagi, Masakuni Degawa |
School of Pharmaceutical Science, University of Shizuoka, Shizuoka, Japan |
| Change of &beta-casein in breast milk before and after relaxation experience by thalassotherapy |
ZYukina Ichiki Yukina , Uehara Masashi , Masuda Miyabi , Takagi Kuniaki , Degawa Masakuni |
School of Pharmaceutical Science, University of Shizuoka, Shizuoka, Japan |
| The effects of tributyltin (TBT) on the mRNA expressions of cytokines in the splenic macrophages and lymphocytes from the F1 rats exposed to TBT |
ZMasashi Tsunoda(1), Takamasa Kido(2), Chiemi Sugaya(1), Hiroshi Katagiri(3), Yoshiharu Aizawa(4) |
(1)Department of Preventive Medicine, Kitasato University School of Medicine, Sagamihara, Japan , (2)Department of Pulic Health and Environmental Medicine, The Jikei University School of Medicine, Tokyo, Japan , (3)Department of Public Health, Kitasato University School of Allied Health Sciences , (4)Kitasato University, Tokyo, Japan |
| Can measuring the expressions of perforin, granzymes and granulysin alternative the assay of NK activity in human peripheral lymphocytes? |
ZQing Li, Maiko Kobayashi, Hirofumi Inagaki, Yoko Wakayama, Masao Katsumata, Yukiyo Hirat , Yingji Li, Kimiko Hirata, Takako Shimizu, Tomoyuki Kawada |
Department of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan |
| Application of Human Cell Line Activation Test (h-CLAT) as a method for detecting allergic potential of drug candidates |
ZMitsuhiro Uchida(1), Toshiyuki Tsuchiya(1), Maho Ukaji(2), Yoshiro Saito(2), Kouichi Kurose(2) |
(1)Toxicology Laboratory, Pharmaceutical research center, Meiji Seika Pharma Co., Ltd., Kanagawa, Japan , (2)Division of Medicinal Safety Science, National Institute of Health Sciences, Tokyo, Japan |
| Students and Young Scientists Session |
| Fetal exposure to carbon nanoparticle altered development of the neonatal immune system |
ZRyuhei Shimizu(1), Masakazu Umezawa(2), Saki Okamoto(1), Rikio Niki(2), Shuhei Ogawa(2),(3), Shiho Watanabe(3), Ryo Abe(3), Ken Takeda(1),(2) |
(1)Department of Hygienic Chemistry, Faculty of Pharmaceutical Science, Tokyo University of Science, Noda, Chiba, Japan , (2)Center of Environmental Health Science Next Generation, RIST, Tokyo University of Science, Noda, Chiba, Japan , (3)Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba, Japan |
| Effect of fetal exposure to carbon black nanoparticle on splenic gene expression in neonatal mouse |
ZMasakazu Umezawa(1), Ryuhei Shimizu(2), Saki Okamoto(2), Shiho Watanabe(3), Shuhei Ogawa(1),(3), Ryo Abe (3), Ken Takeda(1),(2) |
(1)The Center for Environmental Health Science for the Next Generation, RIST, Tokyo University of Science, Noda, Chiba, Japan, (2)Department of Hygienic Chemistry, Faculty of Pharmaceutical Science, Tokyo University of Science, Noda, Chiba, Japan, (3)Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba, Japan |
| The novel immune-modulating effects of amorphous nanosilica particles following epicutaneous exposure |
Toshiro Hirai(1), Yasuo Yoshioka(1), Hedeki Takahashi(1), KO-ichi Ichihashi(1), Nobuo Nishijima(1), Tokuyuki Yoshida(1), Shin-ichi Tsunoda(2),(3), Hiromi Nabeshi(4), Tomoaki Yoshikawa(1), Yasuo Tsutsumi(1),(2),(3) |
(1)Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan , (2)Laboratory of Biopharmaceutical Research, National Institute of Biomedical Innovation (NiBio), Osaka, Japan , (3)MEI center, Osaka University, Osaka, Japan , (4)National Institute of Health Science, Tokyo, Japan |
| Effect of Asian sand dust particles on human airway epithelial cells |
ZYugo Matsuda(1), Akiko Honda(1), Rumiko Murayama(1), Kenshi Tsuji(1), Masataka Nishikawa(2), Eiko Koike(3), Seiichi Yoshida(4), Takamichi Ichinose(4), Hirohisa Takano(1) |
(1)Environmental Health Division, Department of Environmental Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan , (2)Center for Environmental Mesurement and Analysis, National Institute for Environmental Studies, Tsukuba, Japan , (3)Center for Environmental Health Sciences, National Institute for Environmental Studies, Tsukuba, Japan , (4)Department of Health Sciences, Oita University of Nursing and Health Sciences, Oita, japan |
| Luncheon Seminar 1 |
| Evaluation of Anti-Drug Antibodies During Non-Clinical Safety Studies |
Gary Bembridge |
Huntingdon Life Sciences Ltd. |
| Luncheon Seminar 2 |
| Validation and use of several assays to monitor pharmacodynamic markers intended for human use, in the cynomolgus monkey |
Lawrence D Jacob |
Principal Immunologist and Molecular Biologist, Bioanalysis and Immunology Group, Charles River Laboratories Preclinical services, Edinburg |
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