| Plenary Lecture <1> |
| Nanoparticles : a new frontier in particle toxicology |
Professor Ken Donaldson, BSc, PhD, DSc, CBiol, FIBiol, FRCPath, FFOM |
Professor of Respiratory Toxicology, ELEGI Colt Laboratory, Centre for Inflammation Research, Medical School, University of Edinburgh, UK. |
| Plenary Lecture <2> |
| Environment and Nasal Allergy |
Prof. S. Fujieda |
Fukui Medical University, Fukui, Japan |
| Mini Lecture |
| Comparison of the effect of contact sensitizers and chemical - sensitivity inducing substances using cDNA array ayalysis |
Yumiko Nakano |
Osaka Prefectural Institute of Public Health |
| Symposium <1> |
| DEvelopment of guidelines for caring and preveting hazards due to sensitizing chemicals according to a globally harmonized system of classification and labeling of chemicals (GHS) |
Organizer |
Atsushi Ueda |
Preventive and Environmental Medicine, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University |
| Kou Sakabe |
Department of Public Health, Kitasato University School of Pharmaceutical Sciences |
| Globally Harmonized System of classification and labeling of chemicals (GHS)（GHS）；About the classification standard of the chemical and the compound based on influence on health and the environmental impact |
Muneyuki Miyagawa |
Dep. Research Planning , National Institute of Occupational Safety and Health, Institute of Industrial Health, Japan |
| From clinitian's (internal medicine department) standpoint |
Kunio Dobashi |
Depatment of Physical Therapy (Basic Physical Therapy), Allergy - Respiratory Medicine, Gunma University Faculty of Medicine School of Health Sciences |
| Skin disorders with allergic chemical -- Current status and problems of prevention and measures |
Yoko Kataoka |
Department of Dermatology, Osaka Prefectural Medical Center for Respiratory and Allergic Diseases |
| The management of the chemical: From producer's standpoint |
Saburo Nakata |
The Japan Chemical Industry Association |
| Chemical management and GHS by citizen's participation |
Shigeharu Nakachi |
Environmental Monitoring Laboratory (EML), The TOxic Watch Network (T-Watch) |
| Sensitizer in conformity with globally harmonized system GHS (provisional list) |
Kazuhiko Sato |
Department of Environmental Health, School of Medicine, University of Fukui |
| Symposium <2> |
| New Evidence from Animal MOdel for Respiratory Allergy and Nanotoxicology |
Organizer |
Kenzo Takaki |
Nagoya University Schoool of Medicine, School of Health Scieneces |
| Fujio Kayama |
Center for Community Medicine, Division of Environmental Medicine, Jichi Medical School |
| The evaluation of cellular toxicity by using murine alveolar macrophage lineage cells |
Masashi Tsunoda et al |
Kitasato University, School of Medicine, Department of Preventive Medicine and Public Health, Sagamihara, Japan |
| Effect of intratracheal instillation of nanoparticles on chemokine protein release and mRNA expression in lung and lymph node in mice |
Tin-Tin-Win-Shwe et al |
National Institute for Environmental Studies, Tsukuba, Japan |
| Synergistic effect of ultrafine carbon particles on lipoteichoi acid-induced early pulmonary inflammation. |
Shoji Yamamoto et al |
Environmental Health Sciences Division, National Institute for Environmental Studies, Tsukuba, Japan |
| Elevated IgE to Cryptomeria japonica pollen in rats exposed to diesel exhaust during fetus |
Nobue Watanabe |
Department of Environmental Health and Toxicology, Tokyo Metropolitan Institute of Public Health |
| Improving lung function testing in animal to detect allergenicity of inhaled substances |
Dr. Armin Broun |
Immunotoxicology and Immunology/Allergy Dept., Immunology, Allergology and clinical Inhalation Division, Fraunhofer-Institut fur Toxikologie und Experimentelle Medizin ITEM , Hannover, Germany |
| Workshop |
| Non-RI use substitution immunotoxicity examination method: Alternative method of LLNA and NK activity measurement |
Organizer |
Eiji Maki |
Yanssen Pharmaceutical K. K. Tokyo, Japan |
| Jun-ichi Sawada |
Division of Biochemistry and Immunochemistry, National Institute of Health Sciences, Tokyo, Japan |
| Pharmaceuticals Manufacturers Association joint research report concerning LLNA method |
Naohisa Tsutsui |
Mitsubishi Pharma Corporation |
| BrdU method as LLNA substitution method |
Masahito Takeyoshi |
Chemicals Assessment Center, Chemicals Evaluation and Research Institute |
| LLNA-DA method as Non-RI substitution method |
Kunihiko Yamashita |
Daicel Chemical Industries, Ltd., |
| Flow cytometric assay of NK cell function using fluorescence method and its relationship to phenotyping |
Seiji Shibata, Shigeru Hisada |
Safety & Pharmacokinetics Research Department, Teikoku Hormone Mfg.Co., Ltd., Kawasaki, Japan |
| Natural killer cell activity uses fluorochrome |
Ngata M, Kanasaki K, Nakamura K |
Developmental research Laboratories, Shionogi & Co., Ltd., Osaka, Japan |
| General Presentation |
| Examination of T cell dependent antigen in antibody production measurement |
Nagata M, Nakamura K |
Developmental research Laboratories, Shionogi & Co., Ltd., Osaka, Japan |
| Improvement of an enzyme linked immunosorbent assay (ELISA) using whole sheep red blood cell. |
Ai Minakawa et al |
Tsukuba Safety Assessment Laboratories, Banyu Pharmaceutical Co.,Ltd., Ibaragi, Japan |
| Improved whole SRBC-ELISA method for detection of primary antibody response to SRBC in rats |
Hiroshi Watanabe et al |
Tsukuba Safety Assessment Laboratories, Banyu Pharmaceutical Co.,Ltd., Ibaragi, Japan |
| Development of a modified LLNA with non-radio isotopic endpoint. |
Kenji Idehara et al |
Daicel Chemical Industries, LTD |
| Evaluation of the performance of LLNA-DA with known dermal sensitizers. |
Kenji Idehara et al |
Daicel Chemical Industries,LTD. |
| An estimable method of skin sensitization test for metallic medical devices |
Yukiko Kanazawa |
Food and Drug Safety Center, Kanagawa, Japan |
| Murine Food Allergy Model with Oral Sensitization and Oral Challenge(3) |
Tomoko Shindo et al |
Hatano Research Institute, Food and Drug Safety Center, Kanagawa, Japan |
| Effects of indomethacin administered in late-gestation on the development of immune system in rat pups. |
Kiyoshi Kushima, Kenji Hoshino |
Safety Research Laboratories, Yamanouchi Pharmaceutical Co.,Ltd. |
| Effects on immune-response to SRBC-antigen in the immature rats exposed to methoxychlor during the prenatal and postnatal period. |
Koichi Hayashi, Tadashi Kosaka, Yukari Tajima, Hideaki Fujie, Tsutomu Matsumoto, Yasufumi Shutoh and Takanori Harada |
Institure of Environmental Toxicology, Ibaragi, Japan |
| Soy-diet accelerates proteinuria in autoimmune MRL/Mp-lpr/lpr mice |
Zhao Jian-Hong, Sun Su-Ju,Kayama Fujio |
Department of Environmental Medicine, Center for Community Medicine, Jichi Medical School, Tochigi, Japan |
| Alternation of IL-10production in chrisotile-B-resistant human polyclonal T cell line MT-2 |
Yoshie Miura et al |
Department of Hygiene, Kawasaki Medical School, Okayama, Japan |
| Apoptosis-inducing effect of asbestos (chrysotile) on human T cell line (MT-2) and cellular biological changes in sub-line of MT-2, which acquired resistance to chrysotile-induced apoptosis by long-term and low-dose exposure to chrysotile |
Takemi Otsuki et al |
Department of Hygiene, Kawasaki Medical School, Okayama, Japan |
| A case of occupational asthma due to import wood white ash. |
Hitoshi Kobayashi |
The Third of Internal Medicine, School of Medicine, Iwate Medical University, Iwate, Japan |
| Occupation dog allergy |
Atsushi Usami |
Tokai Pollen Institute |
| Development of rhinitis and asthma in occupation allergy |
Atsushi Usami |
Tokai Pollen Institute |
| Assessment of the skin sensitization potential of isocyanates and epoxy compounds using the modified non-RI local lymph node assay. |
Kenji Idehara |
Daicel Chemical Industries,LtD. |
| Airway Inflammatory and Immunological Events in a Rat Model Exposed to Toluene Diisocyanate |
Kui-Cheng Zheng |
Department of Environmental and Preventive Medicine, School of Medicine, University of Ryukyu, Okinawa , Japan |
| Hypersensitivity of mice induced by diisocyanate-Suppressive effects by fasting- |
Nobuhiro Nishio et al |
Department of Hygiene, Kansai Medical University , Osaka, Japan |
| A case of tunneling worker with isocyanate induced asthma |
Kenji Tsushima et al |
First Department of Internal Medicine, Shinshu University School of Medicine, Nagano, Japan |
| Three cases of occupational allergic dermatitis due to epoxy resin |
Ichiro Hara, Kaoru Mitsuya |
Osaka Occupational Health Promotional Center, Osaka, Japan |
| Importance of allergic, immunological management in office that causes occupation allergy |
Susumu Nakamura |
Oita University, Oita, Japan |
| Th1/Th2 balance in mice exposued to Tributyltin oxide |
Kazuo Takahashi et al |
Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan |
| Immunodisruptive effects of arsenic on macrophage generation from human peripheral blood monocytes |
Teruaki Sakurai et al |
Laboratory of Environmental Chemistry, School of Life Science, Tokyo University of Pharmacy and Life Science, Tokyo, Japan |
| Effect of dimethyl2,2-dichlorovinyl phosphate (DDVP) on perforin, granzyme A and granulysin in human NK-92CI cell line |
Qing Li et al |
Department of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan |
| Fundamental studies on effects of 17 β-estradiol on mouse contact dermatitis. |
Humitoshi Sakazaki et al |
Development of Environmental Health, Faculty of Pharmaceutical Sciences, Setsunan University |
| The analysis of Major chemical components of the Japanese ginger and their primary irritation |
Qingjun Wei |
Department of Environmental and Preventive Medicine, Graduate School of Medical Sciences of Kumamoto University, Kumamoto, Japan |
| Survey of food-and inhaled-allergen specific IgE antibody in the sera of children aged three years |
Reiko Teshima et al |
National Institute of Health Sciences, Tokyo, Japan |
| Association of allergic diseases with serum lipid profile and inflammatory markers among healthy workers |
Takaaki Kondo et al |
Nagoya University School of Health Sciences, Nagoya, Japan |
| Evaluation of DNA extraction methods from house dust for the quantitative detection of fungi using real-time PCR analysis |
Yasuo Takeuchi et al |
Clinical research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital |
| A case of hypersensitivity pneumonitis that was present in Shiitake cultivator |
Takashi Mouri et al |
The third department of internal medicine, school of medicine, Iwate Medical University, Iwate, Japan |
| A case of hypersensitivity pneumonitis induced bay Trichoderma viride |
Kitsukawa Y et al |
Pulmonary Medicine & Clinical Immunology, Dokkyo University School of Medicine, Toshigi, Japan |
| Indoor allergen survey in the houses of student in the veterinary medicine |
Akiemi Saito et al |
Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital |
| Cohortostadi of School of Medicine, University of Fukui Fukui of doctor's occupational allerg |
Kato et al |
Department of Environmental Health, School of Medicine, University of Fukui, Fukui, Japan |
| Pathogenesis of seasonal allergic rhinitis under natural allergen provocation |
Kato M et al |
Department of Environmental and Preventive Medicine, Graduate School of Medical Science, Kanazawa University, Ishikawa, Japan |
| Epidemiology of the allergic rhinitis in Taxi Driver |
Nobuyasu Gama |
Dokkyo University school of Medicine, Otolaryngology |
| Epidemiology of pollinosis in middle aged population of a village and a city in Gunma, Japan, related to their lifestyle factors |
Yuriko Hashimoto et al |
Tokyo University of Social Welfare, Tokyo, Japan |
| Clinical Study on Sick House Syndrome and Atopic Dermatitis, with Special Reference to Neuro-Ophthalmological Analysis |
Takako Matsui et al |
Environmental Medical Center, Kitasato Institute Hospital, Tokyo, Japan |
| Luncheon Seminar 1 |
| Drug immunogenicity in non-clinical studies |
Dr. Mark Wing |
Head of Experimental Biology, Senior Immunologist, Huntingdon Life Science Ltd. |
| Luncheon Seminar 2 |
| Preclinical and clinical studies on pharmaceuticals and biopharmaceuticals (including an introduction of the Fraunhofer ITEM) |
Prof. Uwe Heinrich |
Director, Fraunhofer-Institut fur Toxikologie und Experimentelle Medizin ITEM , Hannover, Germany |
| Immunotoxicology in the respiratory tract |
Dr. Armin Broun |
Immunotoxicology and Immunology/Allergy Dept., Immunology, Allergology and clinical Inhalation Division, Fraunhofer-Institut fur Toxikologie und Experimentelle Medizin ITEM , Hannover, Germany |
